Angelina Jolie in Talks to Star in 'Every Note Played'

Angelina Jolie is possibly taking on a new role.

The 45-year-old actress and activist is in talks to star in Every Note Played, an adaptation of Lisa Genova‘s contemporary romance novel, Variety reported Friday (October 9).

PHOTOS: Check out the latest pics of Angelina Jolie

Christoph Waltz is also in talks.

“Jolie will play Karina, the ex-wife of an accomplished concert pianist named Richard (portrayed by Waltz). He has suffered many losses, including the estrangement of his daughter, when he gets diagnosed with ALS in his hands. As the disease worsens and Richard can no longer play the piano or live on his own, Karina reluctantly steps in to be his caregiver,” the outlet reports.

Michael Sucsy is set to direct.

The Maleficent actress recently supported two young boys from London in their effort to help the humanitarian crisis in Yemen with an “extremely generous” donation.